For the first time in American history, one of the leading causes of deaths - vehicle crash - has been supplanted by opioid overdoses. Data, collected in 2017, shows Americans have a 1 in 96 chance of dying from an opioid overdose. The probability of dying in a motor vehicle crash is 1 in 103. Opioid pain relievers are the most fatally abused drugs and they're entirely legal. Roughly 60 people die every day as a result of overdoses from opioids - that's 22,630 Americans.