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As a GMO Pillar Wobbles, Biotech Companies Promise New Insect-Killing Genes

For all the international furor over genetically modified food, or GMOs, the biotech industry has really only managed to put a few foreign genes into food crops. The first of these genes — actually, a small family of similar genes — came from a kind of bacteria called Bacillus thuringiensis, or Bt. Those genes make plants poisonous to certain insect pests. These genes are a pillar of the entire industry. But that pillar is wobbling. Three of the four Bt genes that are supposed to fend off one particularly important pest, the corn rootworm, are showing signs of failure. Corn rootworms have evolved resistance to them. But the biotech companies say not to worry. More genes are on the way. This week, a team of scientists from DuPont Pioneer announced in the journal Sciencethat they'd discovered a new rootworm-killing gene. They found it by searching through the countless bacteria that live in the soil, looking for one that is lethal to the corn rootworm. Many have carried out such searches and failed. The DuPont Pioneer team, however, succeeded. They first found a protein that killed rootworms, then worked backward to find the bacteria and the gene that produced that insecticidal protein. Then they inserted the gene into corn plants. As they'd hoped, it worked. The genetically modified corn plants killed rootworms.

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